Ultrastructural Analysis of Spine Plasticity 11 Ultrastructural Analysis of Spine Plasticity
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چکیده
Dendritic spines are small protrusions that serve as the major site of excitatory synaptic transmission in the brain. The shape and density of spines can be affected by numerous factors, including developmental stage, experimental preparation, temperature, exposure to enriched environments, and neuronal pathology. In addition, physiological models of learning, including long-term potentiation (LTP) and long-term depression (LTD), have indicated that alterations in synaptic ultrastructure may underlie the storage of information in the brain.
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تاریخ انتشار 2008